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data-size=\"normal\"><img loading=\"lazy\" class=\"alignnone size-full wp-image-536\" src=\"http:\/\/hdygyy.com.cn\/wp-content\/uploads\/2020\/10\/v2-c40ea2c94fdceca1e697b46753fa9255_720w-1.jpg\" width=\"720\" height=\"360\" \/><\/figure>\n<p>\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u786e\u5207\u539f\u56e0\u5c1a\u672a\u5b8c\u5168\u4e86\u89e3\u3002\u6211\u4eec\u6240\u77e5\u9053\u7684\u662fCD\u662f\u4e00\u79cd\u590d\u6742\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u5b83\u662f\u7531\u514d\u75ab\u7cfb\u7edf\uff0c\u9057\u4f20\u5b66\uff0c\u80a0\u9053\u7ec6\u83cc\u548c\u73af\u5883\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u5bfc\u81f4\u7684\u3002<\/p>\n<p>5 \u2013 20\uff05\u7684\u60a3\u75c5\u8005\u5177\u6709\u708e\u75c7\u6027\u80a0\u75c5\u7684\u4e00\u7ea7\u7684\u4eb2\u5c5e\u5173\u7cfb\u3002\u5c3d\u7ba1\u5728\u8be5\u9886\u57df\u8fd8\u9700\u8981\u66f4\u591a\u7684\u7814\u7a76\uff0c\u4f46\u4e5f\u5df2\u68c0\u6d4b\u52305\u53f7\u548c10\u53f7\u67d3\u8272\u4f53\u7684\u9057\u4f20\u53d8\u5f02\u3002<\/p>\n<p>\u4e5f\u8bb8\u6700\u503c\u5f97\u6ce8\u610f\u7684\u662fNOD2\u57fa\u56e0\uff0c\u5b83\u4e0eCD\u654f\u611f\u6027\u589e\u52a0\u6709\u5173\u3002\u8be5\u57fa\u56e0\u7684\u6539\u53d8\u88ab\u8ba4\u4e3a\u4f1a\u964d\u4f4e\u80a0\u9053\u7ec6\u80de\u5bf9\u7ec6\u83cc\u7684\u53cd\u5e94\u80fd\u529b\uff0c\u4ece\u800c\u5bfc\u81f4\u514d\u75ab\u7cfb\u7edf\u5bf9\u80a0\u9053\u4e2d\u7684\u7ec6\u83cc\u75c5\u539f\u4f53\u4ea7\u751f\u5f02\u5e38\u53cd\u5e94\u3002<\/p>\n<p>\u8fd9\u79cd\u5f02\u5e38\u7684\u514d\u75ab\u53cd\u5e94\u5b9a\u4e49\u4e86\u81ea\u8eab\u514d\u75ab\uff0c\u6700\u7ec8\u5bfc\u81f4\u4e86\u514b\u7f57\u6069\u75c5\u7684\u6700\u7ecf\u5178\u5f81\u5146\uff1a\u6d88\u5316\u9053\u7684\u6162\u6027\u708e\u75c7\u3002<\/p>\n<p>\u5982\u679c\u514b\u7f57\u6069\u6c0f\u75c5\u662f\u57fa\u56e0\u6b63\u786e\u7684\u4eba\u7684\u514d\u75ab\u7cfb\u7edf\u548c\u80a0\u9053\u7ec6\u83cc\u4e4b\u95f4\u76f8\u4e92\u4f5c\u7528\u7d6e\u4e71\u7684\u7ed3\u679c\u2026\u2026<\/p>\n<p>\u4e3a\u4ec0\u4e48\u4e0d\u662f\u6bcf\u4e2a\u62e5\u6709\u201c\u6b63\u786e\u57fa\u56e0\u201d\u7684\u4eba\u90fd\u60a3\u6709\u514b\u7f57\u6069\u75c5\uff1f<\/p>\n<p>\u8fd9\u662f\u7531\u4e8e\u5916\u90e8\u73af\u5883\u4e5f\u5f71\u54cd\u7740\u57fa\u56e0\u7684\u8868\u8fbe\u3002<\/p>\n<h3><b>\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u6210\u56e0<\/b><\/h3>\n<p>\u5982\u679c\u60a8\u5bf9\u514b\u7f57\u6069\u6c0f\u75c5\u9057\u4f20\u6613\u611f\uff0c\u5219\u4ee5\u4e0b\u56e0\u7d20\u53ef\u4ee5\u6253\u5f00\u6216\u5173\u95ed\u8fd9\u4e9b\u57fa\u56e0\uff1a<\/p>\n<p><b>\u00b7<\/b>\u00a0<b>\u5438\u70df<\/b>\u2013\u5438\u70df\u4e0d\u4ec5\u4f1a\u5bf9\u514b\u7f57\u6069\u6c0f\u75c5\u4ea7\u751f\u8d1f\u9762\u5f71\u54cd\uff0c\u800c\u4e14\u8fd8\u4f1a\u589e\u52a0\u60a3\u4e0a\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u98ce\u9669\u3002\u4e0e\u4e0d\u5438\u70df\u8005\u76f8\u6bd4\uff0c\u5438\u70df\u8005\u66f4\u5bb9\u6613\u590d\u53d1\u5e76\u9700\u8981\u518d\u6b21\u624b\u672f\u3002<\/p>\n<p><b>\u00b7<\/b>\u00a0<b>\u996e\u98df\u548c\u80a0\u6f0f<\/b>\u2013\u996e\u98df\u4e60\u60ef\u4e0d\u826f\u4f1a\u5bfc\u81f4\u80a0\u5185\u7ec6\u83cc\u5931\u8861\uff08\u8425\u517b\u4e0d\u826f\uff09\uff0c\u4ece\u800c\u53ef\u80fd\u5bfc\u81f4\u80a0\u7ba1\u53d7\u635f\u6216\u6e17\u6f0f\uff08\u80a0\u6f0f\uff09\u3002\u7814\u7a76\u4eba\u5458\u8bc1\u5b9e\uff0c\u5728\u7c98\u819c\u708e\u75c7\u53d1\u4f5c\u4e4b\u524d\u53ef\u4ee5\u68c0\u6d4b\u5230\u80a0\u9053\u901a\u900f\u6027\u589e\u52a0\uff08\u6f0f\u6cc4\u7684\u80a0\u9053\uff09\uff0c\u8fd9\u6709\u52a9\u4e8e\u89e3\u91ca\u4e3a\u4ec0\u4e48\u67d0\u4e9b\u4e13\u5bb6\u5c06IBD\u79f0\u4e3a\u201c\u969c\u788d\u6027\u5c4f\u969c\u75be\u75c5(impaired barrier disease)\u201d\u3002<\/p>\n<p><b>\u00b7<\/b>\u00a0<b>\u6297\u751f\u7d20<\/b>\u2013\u6297\u751f\u7d20\u4f1a\u6539\u53d8\u80a0\u9053\u5fae\u751f\u7269\u7ec4\uff0c\u5e76\u4f1a\u5e72\u6270\u4eba\u4f53\u5904\u7406\u591a\u79cd\u7ec6\u83cc\u7684\u80fd\u529b\u3002\u4e00\u9879\u5bf9587\u540d\u514b\u7f57\u6069\u75c5\u60a3\u8005\u7684\u7814\u7a76\u8868\u660e\uff0c\u5728\u786e\u8bca2-5\u5e74\u4e4b\u524d\uff0c\u670971\uff05\u7684\u75c5\u4f8b\u4f7f\u7528\u6297\u751f\u7d20\u3002<\/p>\n<p><b>\u00b7<\/b>\u00a0<b>\u538b\u529b<\/b>-\u57281950\u5e74\u4ee3\uff0cIBD\u88ab\u5f52\u7c7b\u4e3a\u5fc3\u8eab\u75be\u75c5\uff0c\u56e0\u4e3a\u5b83\u4e0e\u60c5\u7eea\uff0c\u538b\u529b\u548c\u5176\u4ed6\u7cbe\u795e\u75c5\u56e0\u7d20\u5bc6\u5207\u76f8\u5173\u3002\u6700\u8fd1\u7684\u7814\u7a76\u8868\u660e\uff0c\u957f\u671f\u7684\u957f\u671f\u538b\u529b\u4f1a\u964d\u4f4e\u514d\u75ab\u7cfb\u7edf\u5e76\u589e\u52a0\u4f53\u5185\u708e\u75c7\u3002\u5176\u4ed6\u8bc1\u636e\u8fd8\u62a5\u544a\u8bf4\u538b\u529b\u662f\u590d\u53d1\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\u3002<\/p>\n<p><b>\u00b7<\/b>\u00a0<b>\u4f4d\u7f6e<\/b>\u2013\u7814\u7a76\u8868\u660e\uff0c\u6700\u4f4e\u7684\u9633\u5149\u7167\u5c04\uff08\u5317\u90e8\u6c14\u5019\uff09\u4e0e\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u53d1\u75c5\u7387\u8f83\u9ad8\u6709\u5173\u3002<\/p>\n<h3><b>\u7ec6\u83cc\u548c\u771f\u83cc\u611f\u67d3-\u5e2e\u52a9\u8bf1\u53d1\u514b\u7f57\u6069\u75c5<\/b><\/h3>\n<p>\u6570\u4ee5\u5343\u8ba1\u7684\u7ec6\u83cc\u751f\u6d3b\u5728\u80a0\u9053\u4e2d\uff0c\u5728\u4e00\u4e2a\u5b8c\u7f8e\u7684\u4e16\u754c\u4e2d\uff0c\u5b83\u4eec\u90fd\u4fdd\u6301\u5e73\u8861\uff08\u5171\u751f\uff09\u3002\u5e73\u8861\u7684\u80a0\u9053\u662f\u5065\u5eb7\u7684\u80a0\u9053\u2013\u708e\u75c7\u548c\u75be\u75c5\u65e0\u6cd5\u63a7\u5236\u3002<\/p>\n<p>\u4f46\u662f\uff0c\u5f53\u8fd9\u79cd\u5e73\u8861\u88ab\u7834\u574f\uff08\u8425\u517b\u4e0d\u826f\uff09\u65f6\uff0c\u7531\u4e8e\u4e0d\u826f\u996e\u98df\u548c\u6297\u751f\u7d20\u7b49\u539f\u56e0\uff0c\u7ec6\u83cc\u548c\u771f\u83cc\u5c06\u6709\u673a\u4f1a\u4fb5\u5165\u5e76\u7ed9\u8eab\u4f53\u9020\u6210\u4e25\u91cd\u7834\u574f\u3002<\/p>\n<p><b>\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4ee5\u4e0b\u771f\u83cc\u548c\u7ec6\u83cc\u5728CD\u4e2d\u8d77\u4f5c\u7528\uff1a<\/b><\/p>\n<p><b><i>\u00b7<\/i><\/b>\u00a0<i><b>\u70ed\u5e26\u5047\u4e1d\u9175\u6bcd\uff08Candida tropicalis\uff09<\/b>\u00a0\u2013<\/i>\u8fd9\u662f\u4e00\u79cd\u771f\u83cc\uff0c\u5c5e\u4e8e\u6211\u4eec\u7684\u5929\u7136\u771f\u83cc\u7ec4\u6216\u771f\u83cc\u5bb6\u65cf\u3002\u5728\u6700\u8fd1\u7684\u4e00\u9879\u7814\u7a76\uff0c\u8fd9\u79cd\u771f\u83cc\u4e0e\u514b\u7f57\u6069\u75c5\u5448\u6b63\u76f8\u5173\uff0c\u5e76\u786e\u5b9a\u4e3a\u4e00\u4e2a\u53ef\u80fd\u7684\u89e6\u53d1\u514b\u7f57\u6069\u75c5\u7684\u8bf1\u56e0\u3002\u7814\u7a76\u4eba\u5458\u8fd8\u53d1\u73b0\uff0c<i>\u70ed\u5e26<\/i>\u5047<i>\u4e1d\u9175\u6bcd<\/i>\u4e0e\u6297<i>\u917f\u9152\u9175\u6bcd<\/i>\u6297\u4f53\u7684\u6c34\u5e73\u76f8\u5173\uff08\u5982\u524d\u6240\u8ff0\uff0c\u5df2\u77e5\u7684CD\u751f\u7269\u6807\u5fd7\u7269\uff09\u3002\u8fd9\u79cd\u65b0\u53d1\u73b0\u5230\u7684\u771f\u83cc\u52a0\u4e0a<i>\u5927\u80a0\u6746\u83cc<\/i>\u548c<i>\u7c98\u8d28\u6c99\u96f7\u6c0f\u83cc\uff0c<\/i>\u8fd9\u4e09\u8005\u5171\u540c\u5f62\u6210\u751f\u7269\u819c\uff0c\u8be5\u751f\u7269\u819c\u53ef\u4ee5\u9644\u7740\u5728\u80a0\u58c1\u4e0a\uff0c\u5f15\u53d1\u708e\u75c7\u5e76\u6700\u7ec8\u5bfc\u81f4\u514b\u7f57\u6069\u6c0f\u75c5\u7684\u75c7\u72b6\u3002<\/p>\n<p><b><i>\u00b7<\/i><\/b>\u00a0<i><b>\u526f\u7ed3\u6838\u5206\u679d\u6746\u83cc\uff08MAP\uff09<\/b>\u00a0\u2013<\/i>\u514b\u7f57\u6069\u75c5\u7814\u7a76\u7684\u6700\u5927\u7a81\u7834\u4e4b\u4e00\u662f\u53d1\u73b0\u4e86MAP\u7ec6\u83cc\u3002\u51e0\u9879\u7814\u7a76\u80fd\u591f\u53d1\u73b0\u8fd9\u79cd\u7ec6\u83cc\u4e0eCD\u4e4b\u95f4\u5b58\u5728\u6b63\u76f8\u5173\uff0c\u5176\u4e2d\u4e00\u9879\u7279\u522b\u662f\u572846\uff05\u7684\u514b\u7f57\u6069\u75c5\u75c5\u4f8b\u4e2d\u68c0\u6d4b\u5230MAP\uff08\u5bf9\u7167\u7ec4\u4e3a20\uff05\uff09\u3002MAP\u975e\u5e38\u5c0f\uff0c\u6709\u65f6\u5bf9\u514d\u75ab\u7cfb\u7edf\u96be\u4ee5\u6349\u6478\u3002\u5b83\u5177\u6709\u8131\u843d\u5916\u5c42\u7684\u80fd\u529b\uff0c\u4f7f\u5f97\u6cbb\u7597\u53d8\u5f97\u66f4\u52a0\u56f0\u96be\u3002\u8fd8\u5df2\u77e5\u5b83\u4f1a\u5f15\u8d77\u725b\u7684\u6162\u6027\u75c5\uff0c\u79f0\u4e3a\u7ea6\u7ff0\u75c5\uff08\u201c Yo-knee&#8217;s\u201d\uff09\uff0c\u5f88\u5bb9\u6613\u901a\u8fc7\u751f\u4e73\u548c\u53d7\u6c61\u67d3\/\u52a0\u5de5\u4e0d\u826f\u7684\u8089\u7c7b\u4ece\u725b\u4f20\u67d3\u7ed9\u4eba\u7c7b\u3002<\/p>\n<p>\u90a3\u4e48\u8fd9\u662f\u4ec0\u4e48\u610f\u601d\uff1f\u8fd9\u610f\u5473\u7740\uff0c\u5982\u679c\u6709\u673a\u4f1a\uff0c\u7ec6\u83cc\u548c\u771f\u83cc\u53ef\u4ee5\u5e2e\u52a9\u5f15\u53d1\u514b\u7f57\u6069\u6c0f\u75c5\u3002\u6211\u4eec\u5e94\u8be5\u505a\u7684\u662f\u6d88\u9664\u8fd9\u4e2a\u673a\u4f1a\u3002<\/p>\n<p>\u7caa\u4fbf\u83cc\u7fa4\u6d4b\u8bd5\u53ef\u4ee5\u5e2e\u52a9\u60a8\u786e\u5b9a\u80a0\u9053\u7684\u5e73\u8861\u7a0b\u5ea6\uff0c\u800c\u76ca\u751f\u83cc\u548c\u6709\u76ca\u4e8e\u80a0\u9053\u7684\u996e\u98df\u53ef\u4ee5\u5e2e\u52a9\u6cbb\u6108\u80a0\u9053\uff08\u5e76\u6700\u7ec8\u5173\u95edCD\u4e2d\u6d89\u53ca\u7684\u81ea\u8eab\u514d\u75ab\u8fc7\u7a0b\uff09\u3002<\/p>\n<h3><b>\u6f0f\u80a0-\u81ea\u8eab\u514d\u75ab\u8fde\u63a5<\/b><\/h3>\n<p>\u5982\u679c\u60a8\u4e00\u76f4\u5728\u5173\u6ce8\u6211\u4eec\u7684\u6587\u7ae0\uff0c\u60a8\u5df2\u7ecf\u77e5\u9053\u51e0\u4e4e\u4e0d\u53ef\u80fd\u5ffd\u7565\u80a0\u9053\u6e17\u6f0f\uff0c\u8fd9\u662f\u81ea\u8eab\u514d\u75ab\u6027\u539f\u56e0<i>\u548c<\/i>\u89e3\u51b3\u65b9\u6848\u7684\u4e00\u90e8\u5206\u3002<\/p>\n<p>\u533b\u5b66\u535a\u58ebAlessio Fasano\u6700\u8fd1\u4e00\u76f4\u5904\u4e8e\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7814\u7a76\u7684\u524d\u6cbf\uff0c\u5e76\u53d1\u8868\u4e86\u4e00\u7bc7\u9898\u4e3a\u201c\u00a0<u>\u6f0f\u80a0\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5<\/u>\u00a0\u201d \u7684\u8bba\u6587\u3002<\/p>\n<p>\u4ed6\u7684\u53d1\u73b0\u63d0\u51fa\u4e86\u4e00\u4e2a\u60f3\u6cd5\uff0c<b>\u4e3a\u4e86\u53d1\u5c55\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u5fc5\u987b\u540c\u65f6\u5b58\u5728\u4e09\u4e2a\u6761\u4ef6\uff1a<\/b><\/p>\n<p>1. \u81ea\u8eab\u514d\u75ab\u7684\u9057\u4f20\u6613\u611f\u6027\uff08\u5373NOD2\u57fa\u56e0\uff09<\/p>\n<p>2. \u66b4\u9732\u4e8e\u73af\u5883\u89e6\u53d1\u56e0\u7d20\uff08\u4f8b\u5982\u5438\u70df\uff09<\/p>\n<p>3. \u80a0\u9053\u901a\u900f\u6027\u589e\u52a0\uff08\u53c8\u79f0\u80a0\u6f0f\uff09<\/p>\n<p>\u53e6\u4e00\u4f4d\u4e13\u5bb6\u4ee5\u8fd9\u79cd\u65b9\u5f0f\u603b\u7ed3\u4e86\u8fd9\u79cd\u8054\u7cfb\uff1a<\/p>\n<p><i>\u80a0\u9053\u6cc4\u6f0f\u7efc\u5408\u5f81\u51e0\u4e4e\u603b\u662f\u4e0e\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u6709\u5173\u3002\u5b9e\u9645\u4e0a\uff0c\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u7684\u9006\u8f6c\u75c7\u72b6\u53d6\u51b3\u4e8e\u80c3\u80a0\u9053\u5185\u58c1\u7684\u6108\u5408\u3002\u4efb\u4f55\u5176\u4ed6\u6cbb\u7597\u65b9\u6cd5\u90fd\u53ea\u662f\u6291\u5236\u75c7\u72b6\u3002\u201d \u2013\u533b\u5b66\u535a\u58ebJill 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